TMEM173 Antibody - middle region

Product Overview

• Article Name: TMEM173 Antibody - middle region
• Biozol Catalog Number: ASB-ARP48041_P050
• Supplier Catalog Number: ARP48041_P050
• Alternative Catalog Number: ASB-ARP48041_P050-25UL,ASB-ARP48041_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Human, Porcine
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TMEM173
• Alternative Names: ERIS, MITA, MPYS, SAVI, NET23, STING, hMITA, hSTING, TMEM173, STING-beta

Product Description

TMEM173 acts as a facilitator of innate immune signaling. It is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. TMEM173 may be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons.It also may be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). TMEM173 mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 42kDa
• NCBI: 340061
• UniProt: Q86WV6
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

WB Suggested Anti-TMEM173 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Hela cell lysate

Host: Rabbit
Target Name: TMEM173
Sample Tissue: Human 786-0 Whole Cell
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: TMEM173
Sample Tissue: Human HepG2 Whole Cell
Antibody Dilution: 1ug/ml

TMEM173 antibody - middle region (ARP48041_P050) in Human HeLa using Western Blot