HADHB Antibody - C-terminal region

Catalog Number: ASB-ARP48133_P050
Article Name: HADHB Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP48133_P050
Supplier Catalog Number: ARP48133_P050
Alternative Catalog Number: ASB-ARP48133_P050-25UL,ASB-ARP48133_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Yeast, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HADHB
Alternative Names: ECHB, MTPB, MSTP029, TP-BETA
HADHB is the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in HADHB gene result in trifunctional protein deficiency. The protein can also bind RNA and decreases the stability of some mRNAs.This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Alternatively spliced transcript variants have been found, however, their full-length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 47kDa
NCBI: 3032
UniProt: P55084
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment.
WB Suggested Anti-HADHB Antibody Titration: 0.25ug/ml
Positive Control: HepG2 cell lysateHADHB is supported by BioGPS gene expression data to be expressed in HepG2
Host: Rabbit
Target Name: HADHB
Sample Tissue: Human A549 Whole Cell
Antibody Dilution: 3ug/ml
HADHB antibody - C-terminal region (ARP48133_P050) in Human HepG2 using Western Blot