P4HB Antibody - N-terminal region
Catalog Number:
ASB-ARP48150_P050
- Images (7)
| Article Name: | P4HB Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP48150_P050 |
| Supplier Catalog Number: | ARP48150_P050 |
| Alternative Catalog Number: | ASB-ARP48150_P050-25UL,ASB-ARP48150_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IHC, WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human P4HB |
| Alternative Names: | DSI, GIT, PDI, PHDB, PDIA1, PO4DB, PO4HB, PROHB, CLCRP1, ERBA2L, P4Hbeta |
| P4HB is the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
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Human kidney |
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WB Suggested Anti-P4HB Antibody Titration: 0.5ug/ml Positive Control: HepG2 cell lysateP4HB is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells |
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Host: Rabbit Target Name: P4HB Sample Tissue: Mouse Pancreas Antibody Dilution: 1ug/ml |
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Host: Mouse Target Name: P4HB Sample Tissue: Mouse Pancreas Antibody Dilution: 1ug/ml |
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Host: Rabbit Target Name: P4HB Sample Tissue: Human HepG2 Whole Cell Antibody Dilution: 1ug/ml |
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Host: Rabbit Target Name: P4HB Sample Tissue: Human MCF7 Whole Cell Antibody Dilution: 1ug/ml |
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P4HB antibody - N-terminal region (ARP48150_P050) in Human HepG2 using Western Blot |
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