PHB2 Antibody - C-terminal region

Product Overview

• Article Name: PHB2 Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP48316_P050
• Supplier Catalog Number: ARP48316_P050
• Alternative Catalog Number: ASB-ARP48316_P050-25UL,ASB-ARP48316_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PHB2
• Alternative Names: BAP, REA, p22, hBAP, Bap37, BCAP37, PNAS-141

Product Description

PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 33kDa
• NCBI: 11331
• UniProt: Q99623
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Rabbit Anti-PHB2 Antibody
Catalog Number: ARP48316_P050
Formalin Fixed Paraffin Embedded Tissue: Human Adult heart
Observed Staining: Cytoplasmic
Primary Antibody Concentration: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy2/3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 a€'' 2.0 sec
Protocol located in Reviews and Data.

Rabbit Anti-PHB2 Antibody
Catalog Number: ARP48316_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Cytoplasmic
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

WB Suggested Anti-PHB2 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysatePHB2 is supported by BioGPS gene expression data to be expressed in HepG2

WB Suggested Anti-PHB2 antibody Titration: 1 ug/mL
Sample Type: Human heart

PHB2 antibody - C-terminal region (ARP48316_P050) in Human HepG2 using Western Blot