PAPSS2 Antibody - C-terminal region

Product Overview

• Article Name: PAPSS2 Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP48642_P050
• Supplier Catalog Number: ARP48642_P050
• Alternative Catalog Number: ASB-ARP48642_P050-25UL,ASB-ARP48642_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PAPSS2
• Alternative Names: SK2, BCYM4, ATPSK2

Product Description

Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3-phosphoadenosine 5-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. PAPSS2 is one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene.Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3-phosphoadenosine 5-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 70kDa
• NCBI: 9060
• UniProt: O95340-2
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

PAPSS2 antibody - C-terminal region (ARP48642_P050)
Catalog Number: ARP48642_P050
Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue
Observed Staining: Cytoplasm of pneumocytes
Primary Antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

PAPSS2 antibody - C-terminal region (ARP48642_P050)
Catalog Number: ARP48642_P050
Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue
Observed Staining: Cytoplasm in hepatocytes
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1/600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

WB Suggested Anti-PAPSS2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 293T cell lysate

Host: Rabbit
Target Name: PAPSS2
Sample Type: Human 721_B
Antibody Dilution: 1.0ug/mlThere is BioGPS gene expression data showing that PAPSS2 is expressed in 721_B

Host: Rabbit
Target Name: PAPSS2
Sample Type: Human Hela
Antibody Dilution: 1.0ug/mlPAPSS2 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells

PAPSS2 antibody - C-terminal region (ARP48642_P050) in Human 293T using Western Blot