QPCT Antibody - middle region

Product Overview

• Article Name: QPCT Antibody - middle region
• Biozol Catalog Number: ASB-ARP48743_P050
• Supplier Catalog Number: ARP48743_P050
• Alternative Catalog Number: ASB-ARP48743_P050-25UL,ASB-ARP48743_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human QPCT
• Alternative Names: QC, GCT, sQC

Product Description

QPCT is responsible for the biosynthesis of pyroglutamyl peptides. QPCT has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. It also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. QPCT may be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 38kDa
• NCBI: 25797
• UniProt: Q16769
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

WB Suggested Anti-QPCT Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Muscle

Host: Rabbit
Target: QPCT
Positive control (+): HepG2 Cell Lysate (HG)
Negative control (-): Human Ovary Tumor (T-OV)
Antibody concentration: 1ug/ml

Host: Rabbit
Target Name: QPCT
Sample Tissue: Human MCF7 Whole Cell
Antibody Dilution: 1ug/ml

QPCT antibody - middle region (ARP48743_P050) in Human Muscle using Western Blot