PGDS Antibody - N-terminal region

Product Overview

• Article Name: PGDS Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP48763_P050
• Supplier Catalog Number: ARP48763_P050
• Alternative Catalog Number: ASB-ARP48763_P050-25UL,ASB-ARP48763_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PGDS
• Alternative Names: GSTS, PGD2, PGDS, GSTS1, GSTS1-1

Product Description

PGDS is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 23kDa
• NCBI: 27306
• UniProt: O60760
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Lung

WB Suggested Anti-PGDS Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Human Spleen

Host: Rabbit
Target Name: HPGDS
Sample Tissue: Human Ovary Tumor
Antibody Dilution: 1ug/ml

Host: Rabbit
Target: HPGDS
Positive control (+): Human lung (LU)
Negative control (-): 293T (2T)
Antibody concentration: 1ug/ml

Surface Plasmon Resonance Kinetic Characterization of Polyclonal Antibody Affinity. Purified polyclonal antibodies were immobilized on a Protein A/G coated Carterra LSA sensor chip (PAGH200M) at concentrations of 5, and 50 ug/mL in duplicate. Antibodies on the surface were exposed to interaction with peptides sequentially via microfluidic controlled flow at 333nM peptide concentration for kinetic characterization of the binders for affinity and specificity, followed by curve fitting using the Kinetics software. Kd determinations for both concentrations were averaged and results and standard deviation are shown.

PGDS antibody - N-terminal region (ARP48763_P050) in Human Spleen using Western Blot