UGT1A7 Antibody - N-terminal region

Article Name:	UGT1A7 Antibody - N-terminal region
Biozol Catalog Number:	ASB-ARP49438_P050
Supplier Catalog Number:	ARP49438_P050
Alternative Catalog Number:	ASB-ARP49438_P050-25UL,ASB-ARP49438_P050-100UL
Manufacturer:	Aviva
Host:	Rabbit
Category:	Proteine/Peptide
Application:	IHC, WB
Species Reactivity:	Human
Immunogen:	The immunogen is a synthetic peptide directed towards the N terminal region of human UGT1A7
Alternative Names:	GNT1, UGT1, UDPGT, UGT1A, UGT1G, UGT-1A, UGT-1G, UGT1.1, UGT1.7, UGT1A1, UGT1-01, UGT1-07, hUG-BR1, UDPGT 1-7

UGT1A7 is an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5 exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has moderate glucuronidase activity with phenols.This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5 exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has moderate glucuronidase activity with phenols. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Clonality:	Polyclonal
Concentration:	0.5 mg/ml
Molecular Weight:	57kDa
NCBI:	54577
UniProt:	Q5DSZ7
Form:	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

	Rabbit Anti-UGT1A7 Antibody Catalog Number: ARP49438_P050 Formalin Fixed Paraffin Embedded Tissue: Human Adult Liver Observed Staining: Cytoplasm in hepatocytes, strong signal, wide tissue distribution Primary Antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 a€'' 2.0 sec Protocol located in Reviews and Data.
	WB Suggested Anti-UGT1A7 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:2500 Positive Control: 721_B cell lysateThere is BioGPS gene expression data showing that UGT1A7 is expressed in 721_B
	Host: Rabbit Target Name: UGT1A7 Sample Tissue: Human OVCAR-3 Whole Cell Antibody Dilution: 1ug/ml
	UGT1A7 antibody - N-terminal region (ARP49438_P050) in Human 721_B using Western Blot