XYLT2 Antibody - C-terminal region

Product Overview

• Article Name: XYLT2 Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP49703_P050
• Supplier Catalog Number: ARP49703_P050
• Alternative Catalog Number: ASB-ARP49703_P050-25UL,ASB-ARP49703_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human XYLT2
• Alternative Names: SOS, XT2, XT-II, PXYLT2, xylT-II

Product Description

XYLT2 is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis.The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 97 kDa
• NCBI: 64132
• UniProt: Q9H1B5
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

WB Suggested Anti-XYLT2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Muscle

25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 0.5 ug/mL of the antibody was used in this experiment. The peptide sequence is present in a ~71 kDa isoform. The protein may be modified by glycosylation.

Host: Rabbit
Target Name: XYLT2
Sample Tissue: Human Jurkat Whole Cell
Antibody Dilution: 1ug/ml

XYLT2 antibody - C-terminal region (ARP49703_P050) in Human Muscle using Western Blot