SPOP Antibody - C-terminal region

Catalog Number: ASB-ARP50348_P050
Article Name: SPOP Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP50348_P050
Supplier Catalog Number: ARP50348_P050
Alternative Catalog Number: ASB-ARP50348_P050-25UL,ASB-ARP50348_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SPOP
Alternative Names: TEF2, BTBD32, NSDVS1, NSDVS2, NEDMACE, NEDMIDF
SPOP may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 42kDa
NCBI: 8405
UniProt: O43791
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-SPOP Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysateSPOP is supported by BioGPS gene expression data to be expressed in HepG2
Host: Rabbit
Target Name: SPOP
Sample Type: Hela
Lane A: Primary Antibody
Lane B: Primary Antibody + Blocking Peptide
Primary Antibody Concentration: 1ug/ml
Peptide Concentration: 5ug/ml
Lysate Quantity: 25ug/lane/lane
Gel Concentration: 0.12
Host: Rabbit
Target Name: SPOP
Sample Tissue: Human MCF7
Antibody Dilution: 1.0ug/ml
Host: Rabbit
Target Name: SPOP
Sample Tissue: Human 293T Whole Cell
Antibody Dilution: 1ug/ml
SPOP antibody - C-terminal region (ARP50348_P050) in Human MCF7 using Western Blot