The immunogen is a synthetic peptide directed towards the C terminal region of human NAGS
Alternative Names:
AGAS, ARGA
NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
Host: Rabbit Target: NAGS Positive control (+): HepG2 Cell Lysate (HG) Negative control (-): Human Ovary Tumor (T-OV) Antibody concentration: 1ug/ml
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. The protein may be modified by acetylation.
NAGS antibody - C-terminal region (ARP51183_T100) in Human HepG2 using Western Blot
* VAT and and shipping costs not included. Errors and price changes excepted