NAGS Antibody - C-terminal region

Catalog Number: ASB-ARP51183_T100
Article Name: NAGS Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP51183_T100
Supplier Catalog Number: ARP51183_T100
Alternative Catalog Number: ASB-ARP51183_T100-25UL,ASB-ARP51183_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NAGS
Alternative Names: AGAS, ARGA
NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 58 kDa
NCBI: 162417
UniProt: Q8N159
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-NAGS Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysate
Host: Rabbit
Target: NAGS
Positive control (+): HepG2 Cell Lysate (HG)
Negative control (-): Human Ovary Tumor (T-OV)
Antibody concentration: 1ug/ml
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. The protein may be modified by acetylation.
NAGS antibody - C-terminal region (ARP51183_T100) in Human HepG2 using Western Blot