CDH1 Antibody - middle region
Catalog Number:
ASB-ARP51289_P050
- Images (4)
| Article Name: | CDH1 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP51289_P050 |
| Supplier Catalog Number: | ARP51289_P050 |
| Alternative Catalog Number: | ASB-ARP51289_P050-25UL,ASB-ARP51289_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IF, IHC, WB |
| Species Reactivity: | Bovine, Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human CDH1 |
| Alternative Names: | UVO, CDHE, ECAD, LCAM, Arc-1, BCDS1, CD324 |
| Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
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Sample Type: Rat FRTL-5 cells Primary Antibody Dilution: 1:100 Secondary Antibody: Goat anti-rabbit-FITC Secondary Antibody Dilution: 1:1000Color/Signal Descriptions: 1A: DAPI, 2B: phase contrast, 2A: CDH1, 2B: DAPI + CDH1Gene Name: CDH1Submitted by: Risheng Ma, MSSM |
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Rabbit Anti-CDH1 Antibody Catalog Number: ARP51289_P050 Formalin Fixed Paraffin Embedded Tissue: Human Thyroid Gland Tissue Observed Staining: Plasma membrane Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
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WB Suggested Anti-CDH1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: 293T cell lysate |
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CDH1 antibody - middle region (ARP51289_P050) in Human 293T using Western Blot |
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