MBNL2 Antibody - middle region

Product Overview

• Article Name: MBNL2 Antibody - middle region
• Biozol Catalog Number: ASB-ARP51632_P050
• Supplier Catalog Number: ARP51632_P050
• Alternative Catalog Number: ASB-ARP51632_P050-25UL,ASB-ARP51632_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MBNL2
• Alternative Names: MBLL, MBLL39, PRO2032

Product Description

MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5ACACCC-3 core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM).

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 28kDa
• NCBI: 10150
• UniProt: O95205
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

WB Suggested Anti-MBNL2 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human brain

Host: Rabbit
Target Name: MBNL2
Sample Type: Hela
Antibody Dilution: 1.0ug/mlThere is BioGPS gene expression data showing that MBNL2 is expressed in HeLa

Host: Rabbit
Target Name: MBNL2
Sample Type: Human Fetal Brain
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: MBNL2
Sample Type: Human Fetal Heart
Antibody Dilution: 1.0ug/ml

MBNL2 antibody - middle region (ARP51632_P050) in Human Brain using Western Blot