COPA Antibody - N-terminal region

Article Name:	COPA Antibody - N-terminal region
Biozol Catalog Number:	ASB-ARP51893_P050
Supplier Catalog Number:	ARP51893_P050
Alternative Catalog Number:	ASB-ARP51893_P050-25UL,ASB-ARP51893_P050-100UL
Manufacturer:	Aviva
Host:	Rabbit
Category:	Proteine/Peptide
Application:	WB
Species Reactivity:	Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Immunogen:	The immunogen is a synthetic peptide directed towards the N terminal region of human COPA
Alternative Names:	AILJK, HEP-COP, alpha-COP

In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone.In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.

Clonality:	Polyclonal
Concentration:	0.5 mg/ml
Molecular Weight:	138 kDa
NCBI:	1314
UniProt:	P53621
Form:	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

	WB Suggested Anti-COPA Antibody Titration: 0.2-1 ug/ml Positive Control: Hela cell lysateCOPA is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells
	Host: Rabbit Target: COPA Positive control (+): Hela (HL) Negative control (-): Human heart (HE) Antibody concentration: 1ug/ml
	25 ug of the indicated Human whole cell or tissue extracts was loaded onto a 6-18% SDS-PAGE gel. 0.5 ug/mL of the antibody was used in this experiment.
	Host: Rabbit Target Name: COPA Sample Type: Hela Whole Cell lysates Antibody Dilution: 3ug/ml
	Host: Rabbit Target Name: COPA Sample Type: Hela Whole Cell lysates Antibody Dilution: 3.0ug/ml
	Host: Rabbit Target Name: COPA Sample Tissue: Human Hela Antibody Dilution: 1.0ug/ml
	COPA Antibody - N-terminal region (ARP51893_P050) in Hela, Human heart using Western Blot