ACTR1B Antibody - C-terminal region

Product Overview

• Article Name: ACTR1B Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP52099_P050
• Supplier Catalog Number: ARP52099_P050
• Alternative Catalog Number: ASB-ARP52099_P050-25UL,ASB-ARP52099_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ACTR1B
• Alternative Names: PC3, ARP1B, CTRN2

Product Description

ACTR1B is a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. ACTR1B, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins are of equal length and share 90% amino acid identity. They are present in a constant ratio of approximately 1:15 in the dynactin complex.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 42kDa
• NCBI: 10120
• UniProt: P42025
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

WB Suggested Anti-ACTR1B Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysateACTR1B is supported by BioGPS gene expression data to be expressed in HepG2

Host: Rabbit
Target Name: ACTR1B
Sample Type: Human 721_B
Antibody Dilution: 1.0ug/mlACTR1B is supported by BioGPS gene expression data to be expressed in 721_B

Host: Rabbit
Target Name: ACTR1B
Sample Type: Human Fetal Brain
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: ACTR1B
Sample Type: Human Fetal Heart
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: ACTR1B
Sample Type: Human Fetal Liver
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: ACTR1B
Sample Type: Human Fetal Lung
Antibody Dilution: 1.0ug/ml

ACTR1B antibody - C-terminal region (ARP52099_P050) in Human HepG2 using Western Blot