HAX1 Antibody - middle region
Catalog Number:
ASB-ARP52141_P050
- Images (4)
| Article Name: | HAX1 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP52141_P050 |
| Supplier Catalog Number: | ARP52141_P050 |
| Alternative Catalog Number: | ASB-ARP52141_P050-25UL,ASB-ARP52141_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IHC, WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human HAX1 |
| Alternative Names: | SCN3, HS1BP1, HCLSBP1 |
| HAX1 is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease.The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. |
|
|
Rabbit Anti-HAX1 Antibody Catalog Number: ARP52141_P050 Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
|
|
WB Suggested Anti-HAX1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: COLO205 cell lysateHAX1 is supported by BioGPS gene expression data to be expressed in COLO205 |
|
|
Host: Mouse Target Name: HAX1 Sample Tissue: Mouse Skeletal Muscle Antibody Dilution: 1ug/ml |
|
|
HAX1 antibody - middle region (ARP52141_P050) in Human COLO205 using Western Blot |
Product Guarantee and Expert Support
