PADI2 Antibody - middle region
Catalog Number:
ASB-ARP52328_P050
- Images (5)
| Article Name: | PADI2 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP52328_P050 |
| Supplier Catalog Number: | ARP52328_P050 |
| Alternative Catalog Number: | ASB-ARP52328_P050-25UL,ASB-ARP52328_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human PADI2 |
| Alternative Names: | PAD2, PDI2, PAD-H19 |
| PADI2 encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. PADI2 is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis.This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
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Host: Rabbit Target Name: PADI2 Sample Type: Hela Whole cell lysates Antibody Dilution: 1.0ug/ml |
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25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. An isoform contains the peptide sequence at 48 kDa. |
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Host: Rabbit Target Name: PADI2 Sample Tissue: Human 293T Whole Cell Antibody Dilution: 1ug/ml |
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Host: Rabbit Target Name: PADI2 Sample Tissue: Human PANC1 Whole Cell Antibody Dilution: 1ug/ml |
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PADI2 antibody - middle region (ARP52328_P050) in Human Hela using Western Blot |
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