CAMKK2 Antibody - N-terminal region

Product Overview

• Article Name: CAMKK2 Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP53184_P050
• Supplier Catalog Number: ARP53184_P050
• Alternative Catalog Number: ASB-ARP53184_P050-25UL,ASB-ARP53184_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CAMKK2
• Alternative Names: CAMKK, CAMKKB

Product Description

CAMKK2 is a calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. CAMKK2 seems to be involved in hippocampal activation of CREB1.The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Seven transcript variants encoding six distinct isoforms have been identified for this gene. Additional splice variants have been described but their full-length nature has not been determined. The identified isoforms exhibit a distinct ability to undergo autophosphorylation and to phosphorylate the downstream kinases.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 55kDa
• NCBI: 10645
• UniProt: Q96RR4
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

WB Suggested Anti-CAMKK2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: 721_B cell lysateThere is BioGPS gene expression data showing that CAMKK2 is expressed in 721_B

Host: Rabbit
Target Name: CAMKK2
Sample Type: Human Adult Placenta
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: CAMKK2
Sample Type: Human HepG2
Antibody Dilution: 1.0ug/mlThere is BioGPS gene expression data showing that CAMKK2 is expressed in HepG2

Host: Rabbit
Target Name: CAMKK2
Sample Type: Human Jurkat
Antibody Dilution: 1.0ug/mlCAMKK2 is supported by BioGPS gene expression data to be expressed in Jurkat

Host: Rabbit
Target Name: CAMKK2
Sample Type: Human MCF7
Antibody Dilution: 1.0ug/mlCAMKK2 is supported by BioGPS gene expression data to be expressed in MCF7

Host: Rabbit
Target Name: CAMKK2
Sample Type: Human Hela
Antibody Dilution: 1.0ug/mlThere is BioGPS gene expression data showing that CAMKK2 is expressed in HeLa

Host: Rabbit
Target Name: CAMKK2
Sample Type: Human Fetal Liver
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: CAMKK2
Sample Tissue: Human A549 Whole Cell
Antibody Dilution: 3ug/ml

CAMKK2 antibody - N-terminal region (ARP53184_P050) in Human 721_B using Western Blot