KLB Antibody - middle region

Product Overview

• Article Name: KLB Antibody - middle region
• Biozol Catalog Number: ASB-ARP53325_P050
• Supplier Catalog Number: ARP53325_P050
• Alternative Catalog Number: ASB-ARP53325_P050-25UL,ASB-ARP53325_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KLB
• Alternative Names: BKL

Product Description

KLB is a single-pass type III membrane protein. It contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. KLB is probably inactive as a glycosidase. It increases the ability of FGFR1 and FGFR4 to bind FGF21.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 120 kDa
• NCBI: 152831
• UniProt: Q86Z14
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Human Testis

Immunohistochemistry of formalin-fixed, paraffin-embedded human testis tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

Immunohistochemistry of formalin-fixed, paraffin-embedded human colon tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

WB Suggested Anti-KLB Antibody Titration: 1 ug/ml
Positive Control: 721_B cell lysate

Host: Rabbit
Target Name: KLB
Sample Tissue: Human U937 Whole Cell
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: KLB
Sample Tissue: Human 786-0 Whole Cell
Antibody Dilution: 1ug/ml

25 ug of the indicated Human whole cell extracts was loaded onto a 6-18% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment.

Host: Rabbit
Target Name: KLOTB
Sample Type: 721_B Whole Cell lysates
Antibody Dilution: 0.5ug/ml

Western Blot