PRKAA1 Antibody - middle region

Product Overview

• Article Name: PRKAA1 Antibody - middle region
• Biozol Catalog Number: ASB-ARP53652_P050
• Supplier Catalog Number: ARP53652_P050
• Alternative Catalog Number: ASB-ARP53652_P050-25UL,ASB-ARP53652_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PRKAA1
• Alternative Names: AMPK, AMPKa1, AMPK alpha 1

Product Description

PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 63kDa
• NCBI: 5562
• UniProt: Q13131
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

WB Suggested Anti-PRKAA1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: COLO205 cell lysate

Sample Type:Arat hepatocyte (50ug)
Priamry Dilution:A1:4000
Secondary Antibody:ADonkey anti-Rabbit HRP
Secondary Dilution:A1:10,000
Image Submitted By:ADustin Singer,
INRA/AgroParistechA

PRKAA1 antibody - middle region (ARP53652_P050) validated by WB using Rat liver and Mouse muscle at 1:1000.

PRKAA1 antibody - middle region (ARP53652_P050) in Human COLO205 using Western Blot