GSN Antibody - C-terminal region

Product Overview

• Article Name: GSN Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP54299_P050
• Supplier Catalog Number: ARP54299_P050
• Alternative Catalog Number: ASB-ARP54299_P050-25UL,ASB-ARP54299_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GSN
• Alternative Names: ADF, AGEL

Product Description

GSN binds to the plus ends of actin monomers and filaments to prevent monomer exchange. It is a calcium-regulated protein, which functions in both assembly and disassembly of actin filaments. Defects in the gene encoding GSN are a cause of familial amyloidosis Finnish type (FAF).The protein encoded by this gene binds to the plus ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 83kDa
• NCBI: 2934
• UniProt: P06396
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

GSN antibody - C-terminal region (ARP54299_P050)
Catalog Number: ARP54299_P050
Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue
Observed Staining: Cytoplasm and membrane of pneumocytes
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1/600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

IHC Information: Paraffin embedded tonsil tissue, tested with an antibody Dilution of 5 ug/ml.

WB Suggested Anti-GSN Antibody Titration: 0.2-1 ug/ml
Positive Control: MCF7 cell lysate

GSN antibody - C-terminal region (ARP54299_P050) validated by WB using pFA fixed human tonsil tissue

GSN antibody - C-terminal region (ARP54299_P050) in Human MCF7 using Western Blot