ARG2 Antibody - C-terminal region

Article Name:	ARG2 Antibody - C-terminal region
Biozol Catalog Number:	ASB-ARP54567_P050
Supplier Catalog Number:	ARP54567_P050
Alternative Catalog Number:	ASB-ARP54567_P050-25UL,ASB-ARP54567_P050-100UL
Manufacturer:	Aviva
Host:	Rabbit
Category:	Proteine/Peptide
Application:	IP, WB
Species Reactivity:	Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
Immunogen:	The immunogen is a synthetic peptide directed towards the C terminal region of human ARG2

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. ARG2 (type II isoform) is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood, it is thought to play a role in nitric oxide and polyamine metabolism.Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood, it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Clonality:	Polyclonal
Concentration:	0.5 mg/ml
Molecular Weight:	39kDa
NCBI:	384
UniProt:	P78540
Form:	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

	ARG2 was immunoprecipitated from 1 mg HEK293 Whole Cell Lysate with ARP54567_P050 with 1:200 dilution. Western blot was performed using ARP54567_P050 at 1/1000 dilution. Lane 1: Control IP in HEK293 Whole Cell Lysate. Lane 2: ARG2 IP with ARP54567_P050 in HEK293 Whole Cell Lysate. Lane 3: Input of HEK293 Whole Cell Lysate.
	WB Suggested Anti-ARG2 Antibody Titration: 0.2-1 ug/ml Positive Control: Jurkat cell lysateARG2 is supported by BioGPS gene expression data to be expressed in Jurkat
	Host: Rabbit Target Name: ARG2 Sample Type: Jurkat Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1ug/ml Peptide Concentration: 5ug/ml Lysate Quantity: 25ug/lane/lane Gel Concentration: 0.12
	Host: Mouse Target Name: ARG2 Sample Tissue: Mouse Pancreas Antibody Dilution: 1ug/ml
	Host: Rabbit Target: ARG2 Positive control (+): MCF7 (N10) Negative control (-): Human liver (LI) Antibody concentration: 1ug/ml
	ARG2 antibody - C-terminal region (ARP54567_P050) in Human Jurkat using Western Blot