GFRA2 Antibody - C-terminal region

Product Overview

• Article Name: GFRA2 Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP54575_P050
• Supplier Catalog Number: ARP54575_P050
• Alternative Catalog Number: ASB-ARP54575_P050-25UL,ASB-ARP54575_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GFRA2
• Alternative Names: NTNRA, RETL2, TRNR2, GDNFRB, NRTNR-ALPHA

Product Description

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. GFRA2 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1.Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 47kDa
• NCBI: 2675
• UniProt: O00451
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

WB Suggested Anti-GFRA2 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human brain

Host: Rabbit
Target Name: GFRA2
Sample Type: Human Adult Placenta
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: GFRA2
Sample Type: Human Fetal Muscle
Antibody Dilution: 1.0ug/ml

GFRA2 antibody - C-terminal region (ARP54575_P050) in Human Brain using Western Blot