GSK3B Antibody - C-terminal region

Product Overview

• Article Name: GSK3B Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP54644_P050
• Supplier Catalog Number: ARP54644_P050
• Alternative Catalog Number: ASB-ARP54644_P050-25UL,ASB-ARP54644_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GSK3B

Product Description

Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. Two isoforms, alpha (GSK3A) and beta, show a high degree of amino acid homology. GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. Two isoforms, alpha (GSK3A, MIM 606784) and beta, show a high degree of amino acid homology (Stambolic and Woodgett, 1994 [PubMed 7980435]). GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation (Plyte et al., 1992 [PubMed 1333807]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 48kDa
• NCBI: 2932
• UniProt: P49841
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Brain, cortex

Rabbit Anti-GSK3B Antibody
Catalog Number: ARP54644_P050
Formalin Fixed Paraffin Embedded Tissue: Human Testis Tissue
Observed Staining: Cytoplasm, Nucleus, Plasma membrane
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

WB Suggested Anti-GSK3B Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: 721_B cell lysateGSK3B is supported by BioGPS gene expression data to be expressed in 721_B

Host: Rabbit
Target Name: GSK3B
Sample Type: Hela
Antibody Dilution: 1.0ug/mlGSK3B is supported by BioGPS gene expression data to be expressed in HeLa

Host: Rabbit
Target Name: GSK3B
Sample Type: Human Fetal Heart
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: GSK3B
Sample Tissue: Mouse Testis
Antibody Dilution: 1ug/ml

Host: Mouse
Target Name: GSK3B
Sample Tissue: Mouse Testis
Antibody Dilution: 1ug/ml

GSK3B antibody - C-terminal region (ARP54644_P050) in Human 721_B using Western Blot