HERV-FRD Antibody - N-terminal region

Product Overview

• Article Name: HERV-FRD Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP56008_P050
• Supplier Catalog Number: ARP56008_P050
• Alternative Catalog Number: ASB-ARP56008_P050-25UL,ASB-ARP56008_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Human
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HERV-FRD
• Alternative Names: envFRD, UNQ6191, ERVFRDE1, GLLL6191, HERV-FRD, HERV-W/FRD

Product Description

Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has retained its original fusogenic properties. HERV-FRD can make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity.Human endogenous retroviruses (HERVs) make up approximately 8% of the human genome. Although most HERVs are nonfunctional, the HERV-W (ERVWE1, MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors (Blaise et al., 2003 [PubMed 14557543]).[supplied by OMIM].

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 60kDa
• NCBI: 405754
• UniProt: P60508
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

WB Suggested Anti-HERV-FRD Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HT1080 cell lysate

Host: Rabbit
Target Name: HERV
Sample Tissue: Human PANC1
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: ERVFRD-1
Sample Tissue: Human PANC1 Whole Cell
Antibody Dilution: 5ug/ml

Host: Rabbit
Target Name: ERVFRD-1
Sample Tissue: Human A549 Whole Cell
Antibody Dilution: 1ug/ml

HERV-FRD antibody - N-terminal region (ARP56008_P050) in Human PANC1 using Western Blot