PIM1 Antibody - N-terminal region

Product Overview

• Article Name: PIM1 Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP56389_P050
• Supplier Catalog Number: ARP56389_P050
• Alternative Catalog Number: ASB-ARP56389_P050-25UL,ASB-ARP56389_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PIM1
• Alternative Names: PIM

Product Description

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 36kDa
• NCBI: 5292
• UniProt: P11309-2
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Host: Rabbit
Target Name: PIM1
Sample Type: Human Fetal Lung
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: PIM1
Sample Tissue: Mouse Heart
Antibody Dilution: 1ug/ml

Host: Mouse
Target Name: PIM1
Sample Tissue: Mouse Heart
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: PIM1
Sample Tissue: Mouse Brain
Antibody Dilution: 1ug/ml

WB Suggested Anti-PIM1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human heart

Host: Rabbit
Target Name: PIM1
Sample Tissue: Mouse Testis
Antibody Dilution: 1ug/ml

Host: Mouse
Target Name: PIM1
Sample Tissue: Mouse Testis
Antibody Dilution: 1ug/ml

Host: Rabbit
Target: PIM1
Positive control (+): Mouse testis (M-TE)
Negative control (-): Mouse brain (M-BR)
Antibody concentration: 1ug/ml

PIM1 antibody - N-terminal region (ARP56389_P050) in Hum. Fetal Lung using Western Blot