PSMB2 Antibody - middle region

Product Overview

• Article Name: PSMB2 Antibody - middle region
• Biozol Catalog Number: ASB-ARP56462_P050
• Supplier Catalog Number: ARP56462_P050
• Alternative Catalog Number: ASB-ARP56462_P050-25UL,ASB-ARP56462_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PSMB2
• Alternative Names: HC7-I

Product Description

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB2 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 23kDa
• NCBI: 5690
• UniProt: P49721
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

WB Suggested Anti-PSMB2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Hela cell lysatePSMB2 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells

Host: Rabbit
Target Name: PSMB2
Sample Type: HepG2
Antibody Dilution: 1.0ug/mlPSMB2 is supported by BioGPS gene expression data to be expressed in HepG2

Host: Rabbit
Target Name: PSMB2
Sample Type: Jurkat
Antibody Dilution: 1.0ug/mlPSMB2 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Host: Rabbit
Target Name: PSMB2
Sample Type: 293T
Antibody Dilution: 1.0ug/mlPSMB2 is supported by BioGPS gene expression data to be expressed in HEK293T

PSMB2 antibody - middle region (ARP56462_P050) in Human HeLa using Western Blot