Tbc1d7 Antibody - C-terminal region, Rabbit, Polyclonal
Catalog Number:
ASB-ARP56927_P050
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| Article Name: | Tbc1d7 Antibody - C-terminal region, Rabbit, Polyclonal |
| Biozol Catalog Number: | ASB-ARP56927_P050 |
| Supplier Catalog Number: | ARP56927_P050 |
| Alternative Catalog Number: | ASB-ARP56927_P050-25UL,ASB-ARP56927_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Tbc1d7 |
| Alternative Names: | 2610009C09Rik |
| Tbc1d7 is a component of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward RHEB in response to alterations in specific cellular growth conditions. The small GTPase RHEB is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB. Participates in the proper sensing of growth factors and glucose, but not amino acids, by mTORC1. It is unclear whether TBC1D7 acts as a GTPase-activating protein and additional studies are required to answer this question. |
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