MTRR Antibody - N-terminal region

Product Overview

• Article Name: MTRR Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP57657_P050
• Supplier Catalog Number: ARP57657_P050
• Alternative Catalog Number: ASB-ARP57657_P050-25UL,ASB-ARP57657_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MTRR
• Alternative Names: MSR, cblE

Product Description

Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 80kDa
• NCBI: 4552
• UniProt: Q9UBK8
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Rabbit Anti-MTRR Antibody
Catalog Number: ARP57657_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Cytoplasmic
Primary Antibody Concentration: N/A
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

WB Suggested Anti-MTRR Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate

WB Suggested Anti-MTRR Antibody Titration: 1ug/ml
Positive Control: Hela cell lysate

Host: Rabbit
Target Name: MTRR
Sample Type: Hela
Lane A: Primary Antibody
Lane B: Primary Antibody + Blocking Peptide
Primary Antibody Concentration: 1ug/ml
Peptide Concentration: 5.0 ug/ml
Lysate Quantity: 25ug/lane/lane
Gel Concentration: 12%MTRR is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells

MTRR antibody - N-terminal region (ARP57657_P050) in Human HepG2 using Western Blot