HMGB2 Antibody - middle region

Catalog Number: ASB-ARP58157_P050
Article Name: HMGB2 Antibody - middle region
Biozol Catalog Number: ASB-ARP58157_P050
Supplier Catalog Number: ARP58157_P050
Alternative Catalog Number: ASB-ARP58157_P050-25UL,ASB-ARP58157_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HMGB2
Alternative Names: HMG2
HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. HMGB2 was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 24kDa
NCBI: 3148
UniProt: P26583
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sample Type: ,NT2 cells
Red: ,Antibody
Blue: ,DAPI
Primary Dilution: ,1ug/50ul antibody
Secondary Antibody: ,Alexa goat anti-rabbit 594
Image Submitted by: ,Yuzhi Chen, University of Arkansas for Medical Sciences  ,
Sample Type:
Human brain stem cellsPrimary Antibody Dilution:
1:500Secondary Antibody:
Goat anti-rabbit Alexa-Fluor 594Secondary Antibody Dilution:
1:1000Color/Signal Descriptions:
HMGB2: Red DAPI:BlueGene Name:
HMGB2Submitted by:
Dr. Yuzhi Chen, University of Arkansas for Medical Science
WB Suggested Anti-HMGB2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Jurkat cell lysateHMGB2 is supported by BioGPS gene expression data to be expressed in Jurkat
Sample Type: 1. Human NT-2 cells (60ug)
Primary Antibody Dilution: ,2ug/ml
Secondary Antibody: IRDye 800CW goat anti-rabbit from Li-COR Bioscience
Secondary Antibody Dilution: ,1: 20,000
Image Submitted by: Yuzhi Chen
University of Arkansas for Medical Science ,
HMGB2 antibody - middle region (ARP58157_P050) in Human Jurkat using Western Blot