The immunogen is a synthetic peptide directed towards the middle region of human HMGB2
Alternative Names:
HMG2
HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. HMGB2 was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sample Type: ,NT2 cells Red: ,Antibody Blue: ,DAPI Primary Dilution: ,1ug/50ul antibody Secondary Antibody: ,Alexa goat anti-rabbit 594 Image Submitted by: ,Yuzhi Chen, University of Arkansas for Medical Sciences  ,
Sample Type: Human brain stem cellsPrimary Antibody Dilution: 1:500Secondary Antibody: Goat anti-rabbit Alexa-Fluor 594Secondary Antibody Dilution: 1:1000Color/Signal Descriptions: HMGB2: Red DAPI:BlueGene Name: HMGB2Submitted by: Dr. Yuzhi Chen, University of Arkansas for Medical Science
WB Suggested Anti-HMGB2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: Jurkat cell lysateHMGB2 is supported by BioGPS gene expression data to be expressed in Jurkat
Sample Type: 1. Human NT-2 cells (60ug) Primary Antibody Dilution: ,2ug/ml Secondary Antibody: IRDye 800CW goat anti-rabbit from Li-COR Bioscience Secondary Antibody Dilution: ,1: 20,000 Image Submitted by: Yuzhi Chen University of Arkansas for Medical Science ,
HMGB2 antibody - middle region (ARP58157_P050) in Human Jurkat using Western Blot
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