GRB2 Antibody - N-terminal region

Product Overview

• Article Name: GRB2 Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP58474_P050
• Supplier Catalog Number: ARP58474_P050
• Alternative Catalog Number: ASB-ARP58474_P050-25UL,ASB-ARP58474_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Alternative Names: ASH, Grb3-3, MST084, NCKAP2, MSTP084, EGFRBP-GRB2

Product Description

The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 24kDa
• NCBI: 2885
• UniProt: P62993
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Rabbit Anti-GRB2 Antibody
Catalog Number: ARP58474_P050
Formalin Fixed Paraffin Embedded Tissue: Human Lymph Node Tissue
Observed Staining: Cytoplasm
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

GRB2 antibody - N-terminal region (ARP58474_P050) validated by WB using 721_B cell Lysate at 1ug/ml.GRB2 is supported by BioGPS gene expression data to be expressed in 721_B

GRB2 antibody - N-terminal region (ARP58474_P050) validated by WB using 1. and 2. Human Cystic Fibrosis Bronchial Epithelial Cells (35ug) Primary Dilution: 1:500Secondary Anitbody: goat anti-rabbit-HRPSecondary Dilution: 1:5000Image Submitted By: Dr. Haouaria BalghiMcGill University

Sample Type:A2. mouse brain extracts (80ug)
Primary Antibody Dilution:A2ug/ml
Secondary Antibody: IRDye 800CW goat anti-rabbit from Li-COR Bioscience
Secondary Antibody Dilution:A1: 20,000
Image Submitted by: Yuzhi Chen
University of Arkansas for Medical ScienceA

Host: Mouse
Target Name: GRB2
Sample Tissue: Mouse Kidney
Antibody Dilution: 1ug/ml

GRB2 antibody - N-terminal region (ARP58474_P050) in Human 721_B using Western Blot