PSMC6 Antibody - C-terminal region

Product Overview

• Article Name: PSMC6 Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP59359_P050
• Supplier Catalog Number: ARP59359_P050
• Alternative Catalog Number: ASB-ARP59359_P050-25UL,ASB-ARP59359_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PSMC6
• Alternative Names: p42, RPT5, SUG2

Product Description

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 44kDa
• NCBI: 5706
• UniProt: P62333
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

WB Suggested Anti-PSMC6 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysate

Lanes:
1: 10ug proteasome fraction from C57B1/6J mouse brain, 2: 10ug proteasome fraction from BLAB/C mouse brain
Primary Antibody Dilution:
1:500
Secondary Antibody:
Anti-rabbit HRP
Secondary Antibody Dilution:
1:5000
Gene Name:
PSMC6
Submitted by:
Dr. Scott Wilson, University of Alabama at Birmingham

Host: Rabbit
Target Name: PSMC6
Sample Type: Human MCF7
Antibody Dilution: 1.0ug/mlPSMC6 is supported by BioGPS gene expression data to be expressed in MCF7

Host: Rabbit
Target Name: PSMC6
Sample Type: Human 721_B
Antibody Dilution: 1.0ug/mlPSMC6 is supported by BioGPS gene expression data to be expressed in 721_B

PSMC6 antibody - C-terminal region (ARP59359_P050) in Human Jurkat using Western Blot