CYP11B1 Antibody - C-terminal region

Product Overview

• Article Name: CYP11B1 Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP60140_P050
• Supplier Catalog Number: ARP60140_P050
• Alternative Catalog Number: ASB-ARP60140_P050-25UL,ASB-ARP60140_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Human, Monkey, Porcine, Sheep
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CYP11B1
• Alternative Names: FHI, CPN1, CYP11B, P450C11

Product Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 58 kDa
• NCBI: 1584
• UniProt: P15538
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment.

Sample Type:
Monkey vagina
Primary Antibody Dilution:
1:25
Secondary Antibody:
Anti-rabbit-HRP
Secondary Antibody Dilution:
1:1000
Color/Signal Descriptions:
Brown: CYP11B1 Blue: Nucleus
Gene Name:
CYP11B1
Submitted by:
Jonathan Bertin, Endoceutics Inc.

Sample Type:
Monkey adrenal gland
Primary Antibody Dilution:
1:25
Secondary Antibody:
Anti-rabbit-HRP
Secondary Antibody Dilution:
1:1000
Color/Signal Descriptions:
Brown: CYP11B1 Blue: Nucleus
Gene Name:
CYP11B1
Submitted by:
Jonathan Bertin, Endoceutics Inc.

WB Suggested Anti-CYP11B1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Liver

Sample type:A1. HEK293TN-GFP-hcyp11B1 (75ug)
2.AHEK293TN-GFP-hcyp11B2 (75ug)
Primary dilution:A1:100
Secondary Antibody:Amouse anti-Rabbit HRP
Secondary Dilution:A1:10,000
Film Exposed for: 5 minutes
Image Submitted by:ACelso Gomez-Sanchez
Mongomery VA Medical Center

Host: Rabbit
Target Name: CYP11B1
Sample Tissue: Human HepG2 Whole Cell
Antibody Dilution: 1ug/ml

CYP11B1 antibody - C-terminal region (ARP60140_P050) in Human Liver using Western Blot