CD63 Antibody - C-terminal region

Product Overview

• Article Name: CD63 Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP60760_P050
• Supplier Catalog Number: ARP60760_P050
• Alternative Catalog Number: ASB-ARP60760_P050-25UL,ASB-ARP60760_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Human
• Alternative Names: MLA1, ME491, LAMP-3, OMA81H, TSPAN30

Product Description

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. The use of alternate polyadenylation sites has been found for this gene.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 26kDa
• NCBI: 967
• UniProt: P08962
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Sample Type: mouse fibroblast lusate (20ug)
Primary Dilution: 1:800 (2% milk)
Secondary Dilution: 1:2000 (5% milk)
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Host: Rabbit
Target Name: CD63
Sample Type: MCF7 Cell lysates
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: CD63
Sample Tissue: Human HCT116 Whole Cell
Antibody Dilution: 1ug/ml

Surface Plasmon Resonance Kinetic Characterization of Polyclonal Antibody Affinity. Purified polyclonal antibodies were immobilized on a Protein A/G coated Carterra LSA sensor chip (PAGH200M) at concentrations of 5, and 50 ug/mL in duplicate. Antibodies on the surface were exposed to interaction with peptides sequentially via microfluidic controlled flow at 333nM peptide concentration for kinetic characterization of the binders for affinity and specificity, followed by curve fitting using the Kinetics software. Kd determinations for both concentrations were averaged and results and standard deviation are shown.

CD63 antibody - C-terminal region (ARP60760_P050) in mouse fibroblast using Western Blot