ZAP70 Antibody - N-terminal region

Product Overview

• Article Name: ZAP70 Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP61186_P050
• Supplier Catalog Number: ARP61186_P050
• Alternative Catalog Number: ASB-ARP61186_P050-25UL,ASB-ARP61186_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Guinea pig, Human, Mouse, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZAP70
• Alternative Names: SRK, STD, TZK, STCD, IMD48, ADMIO2, ZAP-70

Product Description

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 34kDa
• NCBI: 7535
• UniProt: P43403
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

WB Suggested Anti-ZAP70 Antibody
Titration: 1.0 ug/ml
Positive Control: Fetal Lung

Host: Mouse
Target Name: ZAP70
Sample Tissue: Mouse Liver
Antibody Dilution: 1ug/ml

ZAP70 antibody - N-terminal region (ARP61186_P050) in Human Fetal Lung using Western Blot