IL6ST Antibody - middle region

Product Overview

• Article Name: IL6ST Antibody - middle region
• Biozol Catalog Number: ASB-ARP63223_P050
• Supplier Catalog Number: ARP63223_P050
• Alternative Catalog Number: ASB-ARP63223_P050-25UL,ASB-ARP63223_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Rabbit, Rat
• Alternative Names: CD130, GP130, HIES4, CDW130, IL-6RB, sGP130

Product Description

The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 35kDa
• NCBI: 3572
• UniProt: P40189-2
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Rabbit Anti-IL6ST Antibody
Catalog Number: ARP63223_P050
Formalin Fixed Paraffin Embedded Tissue: Human Thyroid Tissue
Observed Staining: Plasma membrane and cytoplasm in follicular cells
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

Rabbit Anti-IL6ST Antibody
Catalog Number: ARP63223_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Plasma membrane
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

WB Suggested Anti-IL6ST Antibody
Titration: 1.0 ug/ml
Positive Control: MDA-MB-435S Whole Cell

Host: Rabbit
Target: IL6ST
Positive control (+): Mouse Kidney (M-KI)
Negative control (-): Mouse Small Intestine (M-IN)
Antibody concentration: 1ug/ml

IL6ST antibody - middle region (ARP63223_P050) in Human MDA-MB-435S using Western Blot