LILRB2 Antibody - C-terminal region

Catalog Number: ASB-ARP63917_P050
Article Name: LILRB2 Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP63917_P050
Supplier Catalog Number: ARP63917_P050
Alternative Catalog Number: ASB-ARP63917_P050-25UL,ASB-ARP63917_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Human
Alternative Names: ILT4, LIR2, CD85D, ILT-4, LIR-2, MIR10, MIR-10
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 65 kDa
NCBI: 10288
UniProt: Q8N423
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-LILRB2 Antibody
Titration: 1.0 ug/ml
Positive Control: Fetal Brain
Host: Rabbit
Target: LILRB2
Positive control (+): Human brain (BR)
Negative control (-): 293T (2T)
Antibody concentration: 1ug/ml
Host: Rabbit
Target Name: LILRB2
Sample Tissue: Human HepG2 Whole Cell
Antibody Dilution: 1ug/ml
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. Recommended dilution for this antibody is 1-3 ug/mL. Recognizes Isoform 1 and Isoform 4 (52 kDa) in some samples.
LILRB2 antibody - C-terminal region (ARP63917_P050) in Human Fetal Brain using Western Blot