WISP2 Antibody - C-terminal region

Product Overview

• Article Name: WISP2 Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP64152_P050
• Supplier Catalog Number: ARP64152_P050
• Alternative Catalog Number: ASB-ARP64152_P050-25UL,ASB-ARP64152_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Canine, Equine, Human, Porcine, Rat
• Alternative Names: CT58, WISP2, CTGF-L

Product Description

This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 24kDa
• NCBI: 8839
• UniProt: O76076
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Host: Rabbit
Target Name: WISP2
Antibody Dilution: 1.0ug/ml
Sample Type: Human Placenta

HeLaWISP2 is supported by BioGPS gene expression data to be expressed in HeLa

WISP2 antibody - C-terminal region (ARP64152_P050) in Human Placenta using Western Blot