EIF3I is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-EIF3I Antibody Titration: 1.0 ug/ml Positive Control: Hela Whole CellEIF3I is supported by BioGPS gene expression data to be expressed in HeLa
Host: Rabbit Target Name: EIF3I Sample Type: Human Hela Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1.0 ug/ml Peptide Concentration: 2.0 ug/ml Lysate Quantity: 25 ug/lane
EIF3I antibody - middle region (ARP64825_P050) in Human HeLa using Western Blot
* VAT and and shipping costs not included. Errors and price changes excepted