NSMCE4A Antibody - C-terminal region

Catalog Number: ASB-ARP70963_P050
Article Name: NSMCE4A Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP70963_P050
Supplier Catalog Number: ARP70963_P050
Alternative Catalog Number: ASB-ARP70963_P050-25UL,ASB-ARP70963_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IF, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human NSMCE4A
Alternative Names: NS4EA, NSE4A, C10orf86
NSMCE4A is a component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). It is involved in positive regulation of response to DNA damage stimulus.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 44kDa
NCBI: 54780
UniProt: Q9NXX6
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sample Type:
HCT116
Primary Antibody Dilution:
4 ug/ml
Secondary Antibody:
Anti-rabbit Alexa 546
Secondary Antibody Dilution:
2 ug/ml
Gene Name:
NSMCE4A
Host: Rabbit
Target Name: NSMCE4A
Sample Type: Fetal Lung lysates
Antibody Dilution: 1.0ug/ml
Host: Rabbit
Target Name: NSMCE4A
Sample Tissue: Human Hela Whole Cell
Antibody Dilution: 0.5ug/ml
Host: Rabbit
Target: NSMCE4A
Positive control (+): HepG2 Cell Lysate (HG)
Negative control (-): A549 Cell Lysate (N03)
Antibody concentration: 0.5ug/ml
NSMCE4A Antibody - C-terminal region (ARP70963_P050) in Fetal Lung using Western Blot