PNP Antibody - middle region, Rabbit, Polyclonal
Catalog Number:
ASB-ARP75005_P050
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| Article Name: | PNP Antibody - middle region, Rabbit, Polyclonal |
| Biozol Catalog Number: | ASB-ARP75005_P050 |
| Supplier Catalog Number: | ARP75005_P050 |
| Alternative Catalog Number: | ASB-ARP75005_P050-25UL,ASB-ARP75005_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | WB |
| Species Reactivity: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of Human PNPH |
| Alternative Names: | NP, PUNP, PRO1837 |
| This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. |
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