IL12B Antibody - middle region

Product Overview

• Article Name: IL12B Antibody - middle region
• Biozol Catalog Number: ASB-ARP80710_P050
• Supplier Catalog Number: ARP80710_P050
• Alternative Catalog Number: ASB-ARP80710_P050-25UL,ASB-ARP80710_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Human
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IL12B
• Alternative Names: CLMF, NKSF, CLMF2, IMD28, IMD29, NKSF2, IL-12B

Product Description

This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 36 kDa
• NCBI: 3593
• UniProt: P29460
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Host: Rabbit
Target Name: IL12B
Sample Tissue: Human DLD1 Whole Cell lysates
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: IL12B
Sample Tissue: Human HT1080 Whole Cell
Antibody Dilution: 3ug/ml

Host: Rabbit
Target Name: IL12B
Sample Tissue: Human HCT116 Whole Cell
Antibody Dilution: 3ug/ml

Host: Rabbit
Target Name: IL12B
Sample Tissue: Human A549 Whole Cell
Antibody Dilution: 0.5ug/ml

Host: Rabbit
Target Name: IL12B
Sample Tissue: Human Jurkat Whole Cell
Antibody Dilution: 3ug/ml

IL12B Antibody - middle region (ARP80710_P050) in Human DLD1 Whole Cell using Western Blot