VRK1 Antibody - C-terminal region
Catalog Number:
ASB-ARP96723_P050
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| Article Name: | VRK1 Antibody - C-terminal region |
| Biozol Catalog Number: | ASB-ARP96723_P050 |
| Supplier Catalog Number: | ARP96723_P050 |
| Alternative Catalog Number: | ASB-ARP96723_P050-25UL,ASB-ARP96723_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human VRK1 |
| Alternative Names: | PCH1, PCH1A |
| Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates Thr-18 of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity. |
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