HOMER2 Antibody - middle region

Product Overview

• Article Name: HOMER2 Antibody - middle region
• Biozol Catalog Number: ASB-ARP96726_P050
• Supplier Catalog Number: ARP96726_P050
• Alternative Catalog Number: ASB-ARP96726_P050-25UL,ASB-ARP96726_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Human
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HOMER2
• Alternative Names: CPD, ACPD, DFNA68, VESL-2, HOMER-2

Product Description

Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses (PubMed:9808459). Required for normal hearing (PubMed:25816005).

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 39 kDa
• NCBI: 9455
• UniProt: Q9NSB8-2
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.