USH1C Antibody - C-terminal region

Product Overview

• Article Name: USH1C Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP96739_P050
• Supplier Catalog Number: ARP96739_P050
• Alternative Catalog Number: ASB-ARP96739_P050-25UL,ASB-ARP96739_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Human
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human USH1C
• Alternative Names: PDZ73, AIE-75, DFNB18, PDZ-45, PDZ-73, PDZD7C, DFNB18A, NY-CO-37, NY-CO-38, ush1cpst, PDZ-73/NY-CO-38

Product Description

Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal development and maintenance of cochlear hair cell bundles (By similarity). As part of the intermicrovillar adhesion complex/IMAC plays a role in brush border differentiation, controlling microvilli organization and length. Probably plays a central regulatory role in the assembly of the complex, recruiting CDHR2, CDHR5 and MYO7B to the microvilli tips.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 46 kDa
• NCBI: 10083
• UniProt: Q9Y6N9-3
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.