MLPH Antibody - middle region
Catalog Number:
ASB-ARP96786_P050
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| Article Name: | MLPH Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP96786_P050 |
| Supplier Catalog Number: | ARP96786_P050 |
| Alternative Catalog Number: | ASB-ARP96786_P050-25UL,ASB-ARP96786_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human MLPH |
| Alternative Names: | SLAC2-A |
| This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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