The immunogen is a synthetic peptide directed towards the middle region of human GTPBP3
Alternative Names:
MSS1, MTGP1, THDF1, GTPBG3, COXPD23
This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.