The immunogen is a synthetic peptide directed towards the middle region of human SENP7
Alternative Names:
sentrin-specific protease 7
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates.