The immunogen is a synthetic peptide directed towards the middle region of human SERPINA1
Alternative Names:
PI, A1A, AAT, PI1, A1AT, nNIF, PRO2275, alpha1AT
The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.