The immunogen is a synthetic peptide directed towards the middle region of human ICAM1
Alternative Names:
BB2, CD54, P3.58
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.